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Blood Group-Bombay !!!

In 1952, 'The Lancet', a research paper from Chikansychology, was the first to describe this blood of Bombay (page: 903-904, 3rd May 1952). In the research paper, Bombay wrote this article on small blood Waii M. Vende, Dr C. Who Patriot and Dr H. M. Bhatia. It is said in the study that if a railway officer and a stabbed person need blood for a day, cross matching with blood donors can be seen that their blood does not match their blood. The three authors of the paper examined blood of 160 people, eventually a cross-match with a local man in Bombay. The blood was first identified in Bombay (now Mumbai). Vende's name gives Bombay blood. In the language of science, it is called hh or blood of the group, after which I say. It is also mentioned in the paper that the blood of this hh group only accepts the blood of the other hh group. After 1952, the real explanation of this blood of Bombay came from many studies. Because the blood of the hH group does not accept any other blood and this blood carrier is very limited, it is said to be the world's most rare blood.


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Now let us know in detail about this blood's scientific explanation of the rareness of blood. To understand the subject of some scientific term in this writing, the readers' blood grouping and blood circulation and Mendel Theory; You can read these two articles. In the first article, you will know how blood grouping is done, in the second article, learn how a trait has shifted from parents to a child. If you understand these two, the scientific explanation about Bombay blood can be easily understood. Now let's know more about how to identify the blood type of blood and how this blood comes in a human family.

Apparently, O group's blood is believed to be a universal donor blood, this blood can be passed to all blood vessels since it does not have Agglutinogen-A or B. O group blood is not easily found during the time of need. But it is more difficult to find the rare blood 'Bombay'. O blood, there is no oligutinization, it is considered relative; However, O group blood has a special type of agglutinogen. Since the presence of this agglutinogen in all the blood contained in the ABO system has been identified, since blood grouping in blood grouping does not take into consideration this agglutinogen. But there is no way in considering the universal agglutinogen in the blood of the hH group, because hh blood is the only blood that does not contain this agglutinogen.

The name of this antigen is Agglutinogen-H. This H antigen is on the surface of red blood cells, like all other antigens responsible for blood grouping. But it has a special quality, it acts as the precursor of the remaining two antigens (Agglutinogen-A and B). 'Precursor' means that, if it achieves appropriate stimulation, it can be transformed into any other substance. For example- we have 7-dehydrocholesterol on our skin. It is made in the liver and is on our skin. Whenever we go to sunlight, due to sunlight stimulation, 7-dehydrocholesterol is converted into the Vitamin-D formation in our body. Since our country gets sunlight almost every year, Vitamin D is produced on the street, for this, we do not need any Vitamin-D meals separately. In the temperate country, in the summer people are sunbathing on the shores of the sea. People in those countries often see vitamin D deficiency. As I was saying, Agglutinogen-H is the precursor of the rest of the two oligutinogenes, that is, from the H-agglutinogen-A and Agglutinogen-B.

Now the question is, who gives H to enthusiasm from H to A and B? In the excitement of H, our genotype, the blue nanoscope in the chromosome's genes, mentions this revival. How it is mentioned, it has been discussed in detail in the previous two articles. If the genotype is written in A or B, then the Agglutinogen will be present in the blood, then only Agglutinogen-H produces Agglutinogen- A or B.

Another question may arise, if the blood does not have Agglutinogen-H, then? That may be, it is not unusual. Many people think that children of A and B group can be O group or not. It may be that even if the blood of this child is possible in any of the four major blood, then Bombay may also be blood if H is absent. However, if both parents are of AB group, and O group blood is found in their child's body, then this child's blood must be of Bombay Group. Because the child from the mother's body is unable to produce that agglutinogen from the genotype of A or B or AB in its genotype, it is possible that the child's blood is O group, and it is only possible if the blood type H is missing.

According to the Mendelian formulas, children with three types of genotype can be born in the body of the above-mentioned parents- HH, Hh, hh. There is no problem with HH or Hh, if the genetic traits are present, enough blood, Agglutinogen-H will be present in the blood.

Only when a hazard occurs, when genotype does not have a manifest gene. HH genotype is not made in the blood due to the manifest genes Agglutinogen-H. Now that the DNA is written in the form of Agglutinogen- A and Agglutinogen-B, the word of creation, from where to be made! The blood is not the processor.



This is why the blood of Bombay is scientifically called the blood of the hh group. How to stimulate the genes, In short, the genes compose the desired transfusion enzyme by compiling the processor to make Agglutinogen-A and B in the blood. If A and B genes are absent, then the H antigen remains in the blood unchanged. We identify it as the blood of O group.

The blood of the hh group is pure (!), There is no adulteration in it. That is, there is no type of agglutinogen in this blood. Therefore, the blood of another group of this group can not be given to the blood of another group. Agglutinin will be produced against all the oligutenojens in the blood due to the presence of any oligutinogen in the blood, if the presence of agglutinogen is found in the blood, it will bind to the whole blood.

This blood of Bombay is always misconstrued as the blood of O group. In our country, the presence of H antigen is never tested in any lab. Maybe at private initiative Different tests of O group blood tests

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